Orphaned by their father's suicide, Nellie and her brother, Jackson, take jobs in the western town of Rita Blanca, where deputy sheriff Jackson is forced to confront six gunfighter brothers and telegrapher Nellie pursues a romance with Buffalo Bill.
After the Civil War, Dal and Mac Traven return home to find the aftermath of a guerrilla rampage of terror. The raiders have the Travens' sister and Dal's girlfriend, Kate, held captive. Now the Travens' are on their trail.